Developmental Biology
Anti-MYT1 Antibody (CAB10824)
- SKU:
- CAB10824
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
| Antibody Name: | Anti-MYT1 Antibody |
| Antibody SKU: | CAB10824 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_004526.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, U-251MG, Mouse liver, Mouse kidney, Rat kidney, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_004526.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KPQD LPSK SVDI EVDE NGTL DLSM HKHR KREN AFPS SSSC SSSP GVKS PDAS QRHS STSA PSSS MTSP QSSQ ASRQ DEWD RPLD YTKP SRLR EEEP EESE PAAH SFAS SEAD DQEV SEEN FEER KYPG EVTL TNFK LKFL SKDI KKEL LTCP TPGC DGSG HITG NYAS HRS |
| Gene ID: | 4661 |
| Uniprot: | Q01538 |
| Cellular Location: | Nucleus |
| Calculated MW: | 122kDa/125kDa |
| Observed MW: | 122kDa |
| Synonyms: | MYT1, C20orf36, MTF1, MYTI, NZF2, PLPB1, ZC2H2C1, ZC2HC4A |
| Background: | The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. |
| UniProt Protein Function: | PLPB1: Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 20q13.33 Cellular Component: cytoplasm; nucleoplasm |
| NCBI Summary: | The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q01538 |
| NCBI GenInfo Identifier: | 13638422 |
| NCBI Gene ID: | 4661 |
| NCBI Accession: | Q01538.2 |
| UniProt Secondary Accession: | Q01538,O94922, Q7Z5W2, Q9UPV2, E1P5H0, F5H7M8, |
| UniProt Related Accession: | Q01538 |
| Molecular Weight: | 125,075 Da |
| NCBI Full Name: | Myelin transcription factor 1 |
| NCBI Synonym Full Names: | myelin transcription factor 1 |
| NCBI Official Symbol: | MYT1 |
| NCBI Official Synonym Symbols: | MTF1; MYTI; NZF2; PLPB1; ZC2H2C1; ZC2HC4A; C20orf36 |
| NCBI Protein Information: | myelin transcription factor 1 |
| UniProt Protein Name: | Myelin transcription factor 1 |
| UniProt Synonym Protein Names: | Myelin transcription factor I; MyTI; PLPB1; Proteolipid protein-binding protein |
| Protein Family: | Myelin transcription factor |
| UniProt Gene Name: | MYT1 |
| UniProt Entry Name: | MYT1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MYT1 antibody (CAB10824) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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