Anti-Musashi-2 (MSI2) Antibody (CAB19814)
- SKU:
- CAB19814
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MSI2H
Description
| Product Name: | Musashi-2 (MSI2) Rabbit mAb |
| Product Code: | CAB19814 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MSI2H |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Musashi-2 (Musashi-2 (MSI2)) |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HT-29, PC-12, MCF7, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human Musashi-2 (Musashi-2 (MSI2)) |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 124540 |
| Uniprot: | Q96DH6 |
| Calculated MW: | 35kDa |
| Observed MW: | 35KDa |
| UniProt Protein Function: | Musashi-2: RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23). Belongs to the Musashi family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: RNA-bindingChromosomal Location of Human Ortholog: 17q22Cellular Component: polysome; cytoplasmMolecular Function: nucleotide binding; poly(U) bindingBiological Process: stem cell development |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96DH6 |
| NCBI GenInfo Identifier: | 20373175 |
| NCBI Gene ID: | 124540 |
| NCBI Accession: | EAW94506 |
| UniProt Secondary Accession: | Q96DH6,Q7Z6M7, Q8N9T4 |
| UniProt Related Accession: | Q96DH6 |
| Molecular Weight: | |
| NCBI Full Name: | RNA-binding protein Musashi homolog 2 isoform a |
| NCBI Synonym Full Names: | musashi RNA-binding protein 2 |
| NCBI Official Symbol: | MSI2 |
| NCBI Official Synonym Symbols: | MSI2H |
| NCBI Protein Information: | RNA-binding protein Musashi homolog 2; musashi-2; musashi homolog 2 |
| UniProt Protein Name: | RNA-binding protein Musashi homolog 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | RNA-binding protein |
| UniProt Gene Name: | MSI2 |
| UniProt Entry Name: | MSI2H_HUMAN |
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