Cell Biology Antibodies 17

Anti-MRPS18C Antibody (CAB18453)

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SKU:
CAB18453
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MRPS18C Antibody
Antibody SKU:CAB18453
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human MRPS18C.
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, HepG2, 293T
Immunogen:Recombinant protein of human MRPS18C.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:51023
Uniprot:Q9Y3D5
Cellular Location:
Calculated MW:
Observed MW:15kDa
Anti-MRPS18C Antibody (CAB18453)Western blot - MRPS18C Rabbit pAb (CAB18453)
Synonyms:CGI-134, MRP-S18-1, MRP-S18-c, MRPS18-1, S18mt-c, mrps18-c, MRPS18C
Background:
UniProt Protein Function:MiscellaneousThere are 3 mitochondrial isoforms of bS18 in mammalia, localizing to 3 distinct sites in the mitoribosome. bS18m (bs18c, this protein) binds to the same site as bacterial bS18, mS40 (bS18b) binds to a novel location of the 28S small subunit, and mL66 (bS18a) binds to the 39S large subunit.
NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]
UniProt Code:Q9Y3D5
NCBI GenInfo Identifier:663071184
NCBI Gene ID:51023
NCBI Accession:NP_001284698.1
UniProt Related Accession:Q9Y3D5
Molecular Weight:16 KD
NCBI Full Name:28S ribosomal protein S18c, mitochondrial isoform 3
NCBI Synonym Full Names:mitochondrial ribosomal protein S18C
NCBI Official Symbol:MRPS18C  
NCBI Official Synonym Symbols:CGI-134; S18mt-c; MRPS18-1; mrps18-c; MRP-S18-1; MRP-S18-c  
NCBI Protein Information:28S ribosomal protein S18c, mitochondrial
UniProt Protein Name:28S ribosomal protein S18c, mitochondrial
UniProt Synonym Protein Names:28S ribosomal protein S18-1, mitochondrial; MRP-S18-1; Mitochondrial small ribosomal subunit protein bS18c
Protein Family:28S ribosomal protein
UniProt Gene Name:MRPS18C  
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