Anti-MRPL28 Antibody (CAB0452)

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SKU:
CAB0452
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MRPL28
Synonyms:
MAAT1
Synonyms:
p15
Synonyms:
mitochondrial ribosomal protein L28
Research Area:
Cell Biology

Description

Product Name:MRPL28 Rabbit mAb
Product Code:CAB0452
Size:20uL, 50uL, 100uL
Synonyms:MRPL28, MAAT1, p15, mitochondrial ribosomal protein L28
Applications:WB, IF, IP
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human MRPL28.
Applications:WB, IF, IP
Recommended Dilutions:WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, 293T, K-562, Mouse kidney, Mouse heart
Immunogen:A synthesized peptide derived from human MRPL28.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:10573
Uniprot:Q13084
Cellular Location:Mitochondrion
Calculated MW:30kDa
Observed MW:30KDa
UniProt Protein Function:MRPL28: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Ribosomal; Mitochondrial; Translation

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nucleoplasm; mitochondrion; cytoplasm; mitochondrial inner membrane; mitochondrial ribosome

Molecular Function:protein binding; structural constituent of ribosome

Biological Process: translation; mitochondrial translation; organelle organization and biogenesis

NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]
UniProt Code:Q13084
NCBI GenInfo Identifier:85695426
NCBI Gene ID:10573
NCBI Accession:Q13084.4
UniProt Secondary Accession:Q13084,Q4TT39, Q96S26, Q9BQD8, Q9BR04, B2RCM4, D3DU46
UniProt Related Accession:Q13084
Molecular Weight:256
NCBI Full Name:39S ribosomal protein L28, mitochondrial
NCBI Synonym Full Names:mitochondrial ribosomal protein L28
NCBI Official Symbol:MRPL28  
NCBI Official Synonym Symbols:p15; MAAT1  
NCBI Protein Information:39S ribosomal protein L28, mitochondrial; L28mt; MRP-L28; melanoma antigen p15; melanoma-associated antigen recognized by T lymphocytes; melanoma-associated antigen recognized by T-lymphocytes; melanoma-associated antigen recognised by cytotoxic T lymphocytes
UniProt Protein Name:39S ribosomal protein L28, mitochondrial
UniProt Synonym Protein Names:Melanoma antigen p15; Melanoma-associated antigen recognized by T-lymphocytes
Protein Family:39S ribosomal protein
UniProt Gene Name:MRPL28  
UniProt Entry Name:RM28_HUMAN
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