Anti-MRPL28 Antibody (CAB0452)
- SKU:
- CAB0452
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MRPL28
- Synonyms:
- MAAT1
- Synonyms:
- p15
- Synonyms:
- mitochondrial ribosomal protein L28
- Research Area:
- Cell Biology
Description
| Product Name: | MRPL28 Rabbit mAb |
| Product Code: | CAB0452 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MRPL28, MAAT1, p15, mitochondrial ribosomal protein L28 |
| Applications: | WB, IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human MRPL28. |
| Applications: | WB, IF, IP |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, K-562, Mouse kidney, Mouse heart |
| Immunogen: | A synthesized peptide derived from human MRPL28. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10573 |
| Uniprot: | Q13084 |
| Cellular Location: | Mitochondrion |
| Calculated MW: | 30kDa |
| Observed MW: | 30KDa |
| UniProt Protein Function: | MRPL28: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; Mitochondrial; Translation Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: nucleoplasm; mitochondrion; cytoplasm; mitochondrial inner membrane; mitochondrial ribosome Molecular Function:protein binding; structural constituent of ribosome Biological Process: translation; mitochondrial translation; organelle organization and biogenesis |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13084 |
| NCBI GenInfo Identifier: | 85695426 |
| NCBI Gene ID: | 10573 |
| NCBI Accession: | Q13084.4 |
| UniProt Secondary Accession: | Q13084,Q4TT39, Q96S26, Q9BQD8, Q9BR04, B2RCM4, D3DU46 |
| UniProt Related Accession: | Q13084 |
| Molecular Weight: | 256 |
| NCBI Full Name: | 39S ribosomal protein L28, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L28 |
| NCBI Official Symbol: | MRPL28 |
| NCBI Official Synonym Symbols: | p15; MAAT1 |
| NCBI Protein Information: | 39S ribosomal protein L28, mitochondrial; L28mt; MRP-L28; melanoma antigen p15; melanoma-associated antigen recognized by T lymphocytes; melanoma-associated antigen recognized by T-lymphocytes; melanoma-associated antigen recognised by cytotoxic T lymphocytes |
| UniProt Protein Name: | 39S ribosomal protein L28, mitochondrial |
| UniProt Synonym Protein Names: | Melanoma antigen p15; Melanoma-associated antigen recognized by T-lymphocytes |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL28 |
| UniProt Entry Name: | RM28_HUMAN |
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