KO Validated Antibodies 2
Anti-MPP2 Antibody (CAB19909)[KO Validated]
- SKU:
- CAB19909
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-MPP2 Antibody [KO Validated] |
Antibody SKU: | CAB19909 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human MPP2. |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T |
Immunogen: | Recombinant protein of human MPP2. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 4355 |
Uniprot: | Q14168 |
Cellular Location: | |
Calculated MW: | 46kDa/60kDa/61kDa/63kDa/64kDa/66kDa |
Observed MW: | 65KDa |
Synonyms: | MPP2, DLG2 |
Background: | Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. |
UniProt Protein Function: | MPP2: a protein of the MAGUK family. Contains one guanylate kinase-like domain, one SH3 domain, one PDZ domain, and two L27 domains. L27 domains are foun CASK in receptor targeting proteins including Lin-2, -4, -5, -6 and -7C, as well as the protein kinases. Three isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 17q12-q21 Cellular Component: membrane; integral to plasma membrane Molecular Function:guanylate kinase activity; PDZ domain binding Biological Process: signal transduction; nucleotide phosphorylation |
NCBI Summary: | Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14168 |
NCBI GenInfo Identifier: | 290457681 |
NCBI Gene ID: | 4355 |
NCBI Accession: | Q14168.3 |
UniProt Secondary Accession: | Q14168,Q53ES9, Q5CZB9, Q9BQJ2, B4DGE9, B4DRJ0, B7Z3G8 E7EV80, E7EV91, E7EX01, |
UniProt Related Accession: | Q14168 |
Molecular Weight: | 576 |
NCBI Full Name: | MAGUK p55 subfamily member 2 |
NCBI Synonym Full Names: | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
NCBI Official Symbol: | MPP2 |
NCBI Official Synonym Symbols: | DLG2 |
NCBI Protein Information: | MAGUK p55 subfamily member 2; discs large, homolog 2 |
UniProt Protein Name: | MAGUK p55 subfamily member 2 |
UniProt Synonym Protein Names: | Discs large homolog 2; Protein MPP2 |
Protein Family: | MAGUK p55 subfamily |
UniProt Gene Name: | MPP2 |
UniProt Entry Name: | MPP2_HUMAN |