Anti-Mouse EpCAM (CD326) In Vivo Antibody - Low Endotoxin
- SKU:
- IVMB0255
- Product Type:
- Hybridoma Monoclonal Antibody
- Clone:
- G8.8
- Protein:
- EpCAM
- Isotype:
- Rat IgG2a k
- Reactivity:
- Human
- Reactivity:
- Mouse
- Synonyms:
- EGP314
- Research Area:
- Cell Adhesion
- Research Area:
- Immunology
- Endotoxin Level:
- Low Endotoxin
- Host Species:
- Rat
- Applications:
- FC
- Applications:
- IF
- Applications:
- IHC
- Applications:
- IP
- Applications:
- WB
Description
| Product Name: | Anti-Mouse EpCAM (CD326) In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0255 |
| Size: | 1 mg, 5 mg, 25 mg, 50 mg, 100 mg |
| Clone: | G8.8 |
| Product Type: | Hybridoma Monoclonal Antibody |
| Synonyms: | EGP314 |
| Isotype: | Rat IgG2a k |
| Reactivity: | Human, Mouse |
| Applications: | FC, IF, IHC, IP, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% by SDS Page ⋅ ≥95% monomer by analytical SEC |
| Product Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Applications: | FC, IF, IHC, IP, WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rat |
| Specificity: | G8.8 activity is directed against mouse EpCAM (CD326) and does not recognize human or rat EpCAM. |
| Antigen Distribution: | EpCAM is expressed in many epithelial tissues from very early embryos to adult animals and is a cell surface marker on various stem and progenitor cells. EpCAM is also an important carcinoma marker highly expressed on a variety of carcinomas, including epithelial tumors and acute myeloid leukemia. EpCAM is enriched in the basolateral membrane of mouse and human intestinal epithelium and is localized to tight junctions, adherens junctions, and the lateral membranes of epithelial cells lining the intestines. |
| Immunogen: | TE-71 thymic epithelial cell line |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. |
| Purity: | ≥95% by SDS Page ⋅ ≥95% monomer by analytical SEC |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -70°C. Avoid Repeated Freeze Thaw Cycles. |
| Ligand/Receptor: | LAIR-1 (CD305) and LAIR-2 (CD306) |
| Research Area: | Cell Adhesion, Immunology |
| State of Matter: | Liquid |
| Shipping: | 2-8°C |
| NCBI Gene Bank ID: | 17075 |
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