Cell Death Antibodies 1
Anti-MIEN1 Antibody (CAB15535)
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- SKU:
- CAB15535
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-MIEN1 Antibody |
| Antibody SKU: | CAB15535 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human MIEN1 (NP_115715.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human MIEN1 (NP_115715.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSGE PGQT SVAP PPEE VEPG SGVR IVVE YCEP CGFE ATYL ELAS AVKE QYPG IEIE SRLG GTGA FEIE INGQ LVFS KLEN GGFP YEKD LIEA IRRA SNGE TLEK ITNS RPPC VIL |
| Gene ID: | 84299 |
| Uniprot: | Q9BRT3 |
| Cellular Location: | Cell membrane, Cytoplasm, Cytoplasmic side, Lipid-anchor, cytosol |
| Calculated MW: | 12kDa |
| Observed MW: | 15kDa |
| Synonyms: | MIEN1, C17orf37, C35, ORB3, RDX12, XTP4 |
| Background: |
| UniProt Protein Function: | MIEN1: Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. Belongs to the SelWTH family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q12 Cellular Component: cytoplasm; cytosol; nucleoplasm Molecular Function:protein binding Biological Process: apoptosis; negative regulation of apoptosis; positive regulation of cell migration; positive regulation of filopodium formation |
| UniProt Code: | Q9BRT3 |
| NCBI GenInfo Identifier: | 29468235 |
| NCBI Gene ID: | |
| NCBI Accession: | AF490253.1 |
| Molecular Weight: | 12,403 Da |
| NCBI Full Name: | Homo sapiens XTP4 (XTP4) mRNA, complete cds |
| UniProt Protein Name: | Migration and invasion enhancer 1 |
| UniProt Synonym Protein Names: | HBV X-transactivated gene 4 protein; HBV XAg-transactivated protein 4; Protein C35 |
| UniProt Gene Name: | MIEN1 |
| UniProt Entry Name: | MIEN1_HUMAN |
 | Western blot analysis of extracts of 293T cells, using MIEN1 antibody (CAB15535) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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