Cell Biology Antibodies 2
Anti-MICU2 Antibody (CAB12198)
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- SKU:
- CAB12198
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MICU2 Antibody |
| Antibody SKU: | CAB12198 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human MICU2 (NP_689939.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, U-87MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human MICU2 (NP_689939.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AWHH SRVS VAAR DGSF TVSA QKNV EHGI IYIG KPSL RKQR FMQF SSLE HEGE YYMT PRDF LFSV MFEQ MERK TSVK KLTK KDIE DTLS GIQT AGCG STFF R |
| Gene ID: | 221154 |
| Uniprot: | Q8IYU8 |
| Cellular Location: | Mitochondrion intermembrane space |
| Calculated MW: | 49kDa |
| Observed MW: | 45KDa |
| Synonyms: | MICU2, 1110008L20Rik, EFHA1 |
| Background: |
| UniProt Protein Function: | MICU2: Involved in mitochondrial uniporter-mediated calcium uptake. Probable regulator of the mitochondrial calcium uniporter (MCU). Component of a complex, at least composed of MCU, MICU1 and MICU2 |
| UniProt Protein Details: | Protein type:Calcium-binding; Mitochondrial Chromosomal Location of Human Ortholog: 13q12.11 Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; nucleus Molecular Function:protein binding; protein heterodimerization activity Biological Process: mitochondrial calcium ion homeostasis; mitochondrial calcium ion transport; reduction of mitochondrial calcium ion concentration |
| UniProt Code: | Q8IYU8 |
| NCBI GenInfo Identifier: | 115502157 |
| NCBI Gene ID: | 221154 |
| NCBI Accession: | Q8IYU8.2 |
| UniProt Secondary Accession: | Q8IYU8,Q8N0T6, Q8NAX8, |
| UniProt Related Accession: | Q8IYU8 |
| Molecular Weight: | 50kDa |
| NCBI Full Name: | Calcium uptake protein 2, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial calcium uptake 2 |
| NCBI Official Symbol: | MICU2 |
| NCBI Official Synonym Symbols: | EFHA1; 1110008L20Rik |
| NCBI Protein Information: | calcium uptake protein 2, mitochondrial |
| UniProt Protein Name: | Calcium uptake protein 2, mitochondrial |
| UniProt Synonym Protein Names: | EF-hand domain-containing family member A1 |
| Protein Family: | Calcium uptake protein |
| UniProt Gene Name: | MICU2 |
 | Western blot analysis of extracts of various cell lines, using MICU2 Rabbit pAb (CAB12198) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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