MIB1/DIP1 Rabbit Monoclonal Antibody (CAB3371)

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SKU:
CAB3371
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Reactivity:
Human, Mouse, Rat
Synonyms:
MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2, MIB1/DIP1
Frequently bought together:

Description

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MIB1/DIP1 Monoclonal Antibody (CAB3371)

The MIB1/DIP1 Monoclonal Antibody (CAB3371) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed by Assay Genie, is highly specific and reactive with human samples, making it ideal for use in various research applications such as immunohistochemistry and Western blotting.The MIB1 protein, also known as Mind bomb 1, is a critical regulator of Notch signaling and is involved in various cellular processes such as differentiation and development. Dysregulation of MIB1 has been linked to cancer and other diseases, making it an important target for therapeutic intervention.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MIB1/DIP1 Monoclonal Antibody
SKU:CAB3371
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Clone Number:ARC1958
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MSNS RNNR VMVE GVGA RVVR GPDW KWGK QDGG EGHV GTVR SFES PEEV VVVW DNGT AANY RCSG AYDL RILD SAPT GIKH DGTM CDTC RQQP IIGI RWKC
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2, MIB1/DIP1
Positive Sample:293T, K-562, Mouse lung, Mouse testis, Mouse brain, Rat brain
Cellular Localization:Cell Membrane, Cytoplasm, Centriolar Satellite, Centrosome, Cytoskeleton, Microtubule Organizing Center.
Calculated MW:110kDa
Observed MW:110kDa

This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).

Purification MethodAffinity purification
Gene ID57534
RRIDAB_2863045
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using MIB1/DIP1 Rabbit mAb (CAB3371) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
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