Signal Transduction Antibodies 1
Anti-MESP1 Antibody (CAB10148)
- SKU:
- CAB10148
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-MESP1 Antibody |
| Antibody SKU: | CAB10148 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 149-268 of human MESP1 (NP_061140.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:1000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, HeLa, THP-1, Mouse heart, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 149-268 of human MESP1 (NP_061140.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RRCR QRGD AGSP RGCP LCPD DCPA QMQT RTQA EGQG QGRG LGLV SAVR AGAS WGSP PACP GARA APEP RDPP ALFA EAAC PEGQ AMEP SPPS PLLP GDVL ALLE TWMP LSPL EWLP EEPK |
| Gene ID: | 55897 |
| Uniprot: | Q9BRJ9 |
| Cellular Location: | Nucleus |
| Calculated MW: | 28kDa |
| Observed MW: | 20kDa |
| Synonyms: | MESP1, bHLHc5 |
| Background: |
| UniProt Protein Function: | MESP1: Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Transcription factor Chromosomal Location of Human Ortholog: 15q26.1 Cellular Component: nucleus Molecular Function:transcription factor activity Biological Process: cardiac muscle cell differentiation; endothelial cell differentiation; gastrulation; heart looping; lateral mesoderm development; negative regulation of endodermal cell fate specification; negative regulation of mesodermal cell fate specification; negative regulation of transcription, DNA-dependent; neurogenesis; positive regulation of Notch signaling pathway; positive regulation of striated muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent |
| UniProt Code: | Q9BRJ9 |
| NCBI GenInfo Identifier: | 74732894 |
| NCBI Gene ID: | 55897 |
| NCBI Accession: | Q9BRJ9.1 |
| UniProt Secondary Accession: | Q9BRJ9,Q9NSF1, Q9NSF2, |
| UniProt Related Accession: | Q9BRJ9 |
| Molecular Weight: | 28,501 Da |
| NCBI Full Name: | Mesoderm posterior protein 1 |
| NCBI Synonym Full Names: | mesoderm posterior bHLH transcription factor 1 |
| NCBI Official Symbol: | MESP1 |
| NCBI Official Synonym Symbols: | bHLHc5 |
| NCBI Protein Information: | mesoderm posterior protein 1 |
| UniProt Protein Name: | Mesoderm posterior protein 1 |
| UniProt Synonym Protein Names: | Class C basic helix-loop-helix protein 5; bHLHc5 |
| Protein Family: | Mesoderm posterior protein |
| UniProt Gene Name: | MESP1 |
| UniProt Entry Name: | MESP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MESP1 antibody (CAB10148) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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