Anti-MEPE Antibody (CAB9559)
- SKU:
- CAB9559
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MEPE
- Synonyms:
- OF45
Description
| Product Name: | MEPE Rabbit pAb |
| Product Code: | CAB9559 |
| Size: | 100uL |
| Synonyms: | MEPE, OF45 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic Peptide of human MEPE |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, Mouse liver, Mouse spinal cord, Rat brain, Rat liver |
| Immunogen: | A synthetic Peptide of human MEPE |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 56955 |
| Uniprot: | Q9NQ76 |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
| Calculated MW: | 45kDa/58kDa/62kDa |
| Observed MW: | 58KDa |
| UniProt Protein Function: | MEPE: Promotes renal phosphate excretion and modulates mineralization. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 4q21.1 Molecular Function:extracellular matrix structural constituent; protein binding Biological Process: biomineral formation; skeletal development |
| NCBI Summary: | This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Code: | Q9NQ76 |
| NCBI GenInfo Identifier: | 33112396 |
| NCBI Gene ID: | 56955 |
| NCBI Accession: | Q9NQ76.1 |
| UniProt Secondary Accession: | Q9NQ76,A1A4X9, A8MTA3, D2CFR4, F5H5C5, |
| UniProt Related Accession: | Q9NQ76 |
| Molecular Weight: | 45,291 Da |
| NCBI Full Name: | Matrix extracellular phosphoglycoprotein |
| NCBI Synonym Full Names: | matrix extracellular phosphoglycoprotein |
| NCBI Official Symbol: | MEPE |
| NCBI Official Synonym Symbols: | OF45 |
| NCBI Protein Information: | matrix extracellular phosphoglycoprotein |
| UniProt Protein Name: | Matrix extracellular phosphoglycoprotein |
| UniProt Synonym Protein Names: | Osteoblast/osteocyte factor 45; OF45 |
| Protein Family: | Matrix extracellular phosphoglycoprotein |
| UniProt Gene Name: | MEPE |
| UniProt Entry Name: | MEPE_HUMAN |
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