MEF2A+MEF2C Rabbit Monoclonal Antibody (CAB2710)

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SKU:
CAB2710
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
Reactivity:
Human, Mouse
Synonyms:
NEDHSIL, DEL5q14.3, C5DELq14.3, mef2, ADCAD1, RSRFC4, RSRFC9, MEF2A+MEF2C
Research Use:
Cell Death
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

MEF2A+MEF2C Monoclonal Antibody (CAB2710)

The MEF2A+MEF2C Monoclonal Antibody (CAB2710) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in Western blot applications.MEF2A and MEF2C play important roles in cell differentiation, growth, and survival, making them critical targets for research in developmental biology, neurobiology, and cardiac biology. The antibody binds to MEF2A and MEF2C proteins, allowing for their detection and analysis in different cell types and tissues.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:MEF2A+MEF2C Monoclonal Antibody
SKU:CAB2710
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC2661
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:NRKP DLRV LIPP GSKN TMPS VSED VDLL LNQR INNS QSAQ SLAT PVVS VATP TLPG QGMG GYPS AIST TYGT EYSL SSAD LSSL SGFN TASA LHLG SVTG WQQQ HLHN MPPS ALSQ LGAC TSTH LSQS SNLS LPST QSLN IKSE PVSP PRDR TTTP SRYP QHTR HEAG RSPV DSLS SCSS SYDG SDRE DHRN EFHS PIGL TRPS PDER ESPS VKRM RLSE GWAT
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NEDHSIL, DEL5q14.3, C5DELq14.3, mef2, ADCAD1, RSRFC4, RSRFC9, MEF2A+MEF2C
Positive Sample:RD, Mouse brain
Cellular Localization:Cytoplasm, Cytosol, Nuclear Speck, Nucleoplasm, Nucleus, Sarcoplasm.
Calculated MW:51kDa
Observed MW:51kDa/54kDa

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID4208 4205
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using MEF2A+MEF2C Rabbit mAb (CAB2710) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon carcinoma using MEF2A+MEF2C Rabbit mAb (CAB2710) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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