Epigenetics & Nuclear Signaling Antibodies 3

MED1 Rabbit Polyclonal Antibody (CAB1724)

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SKU:
CAB1724
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Synonyms:
PBP, CRSP1, RB18A, TRIP2, PPARBP, CRSP200, DRIP205, DRIP230, PPARGBP, TRAP220, MED1
Research Use:
Epigenetics and Nuclear Signaling
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Description

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MED1 Antibody (CAB1724)

The MED1 Antibody (CAB1724) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Med1 protein, this antibody facilitates the detection and analysis of Med1 in different cell types, making it an essential component in studies related to gene regulation, cell signaling, and cancer research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:MED1 Antibody
SKU:CAB1724
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MKAQ GETE ESEK LSKM SSLL ERLH AKFN QNRP WSET IKLV RQVM EKRV VMSS GGHQ HLVS CLET LQKA LKVT SLPA MTDR LESI ARQN GLGS HLSA SGTE CYIT SDMF YVEV QLDP AGQL CDVK VAHH GENP VSCP ELVQ QLRE KNFD EFSK HLKG LVNL YNLP GDNK LKTK MYLA LQSL EQDL SKMA IMYW KATN AGPL DKIL HGSV GYLT PRSG GHLM NLKY YVSP SDLL DDKT ASPI ILHE NNVS RSLG MNAS VTIE GTSA VYKL PIAP LIMG SHPV DNKW TPSF SSIT SANS VDLP
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PBP, CRSP1, RB18A, TRIP2, PPARBP, CRSP200, DRIP205, DRIP230, PPARGBP, TRAP220, MED1
Positive Sample:MCF7
Cellular Localization:Nucleus.
Calculated MW:168kDa
Observed MW:250kDa

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.

Purification MethodAffinity purification
Gene ID5469
RRIDAB_2763774
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from MCF7 cells, using MED1 Rabbit pAb (CAB1724) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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