Signal Transduction Antibodies 1

Anti-MB Antibody (CAB13326)

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SKU:
CAB13326
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-MB Antibody
Antibody SKU:CAB13326
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human MB (NP_005359.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:BT-474, 22Rv1, HepG2, Mouse liver, Mouse skeletal muscle
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human MB (NP_005359.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGLS DGEW QLVL NVWG KVEA DIPG HGQE VLIR LFKG HPET LEKF DKFK HLKS EDEM KASE DLKK HGAT VLTA LGGI LKKK GHHE AEIK PLAQ SHAT KHKI PVKY LEFI SECI IQVL QSKH PGDF GADA QGAM NKAL ELFR KDMA SNYK ELGF QG
Gene ID:4151
Uniprot:P02144
Cellular Location:
Calculated MW:17kDa
Observed MW:15kDa
Synonyms:MB, PVALB, myoglobgin, myoglobin
Background:This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported.
UniProt Protein Function:MB: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Belongs to the globin family.
UniProt Protein Details:

Protein type:Carrier

Chromosomal Location of Human Ortholog: 22q13.1

Molecular Function:iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: slow-twitch skeletal muscle fiber contraction; response to hydrogen peroxide; oxygen transport; heart development; response to hormone stimulus; brown fat cell differentiation; response to hypoxia; enucleate erythrocyte differentiation

NCBI Summary:This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
UniProt Code:P02144
NCBI GenInfo Identifier:127661
NCBI Gene ID:4151
NCBI Accession:P02144.2
UniProt Secondary Accession:P02144,Q52H51, Q5THY7,
UniProt Related Accession:P02144
Molecular Weight:17,184 Da
NCBI Full Name:Myoglobin
NCBI Synonym Full Names:myoglobin
NCBI Official Symbol:MB  
NCBI Official Synonym Symbols:PVALB; myoglobgin  
NCBI Protein Information:myoglobin
UniProt Protein Name:Myoglobin
Protein Family:Myoglobin
UniProt Gene Name:MB  
UniProt Entry Name:MYG_HUMAN
Anti-MB Antibody (CAB13326)Western blot analysis of extracts of various cell lines, using MB antibody (CAB13326) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
Anti-MB Antibody (CAB13326)Immunofluorescence analysis of A-549 cells using MB antibody (CAB13326). Blue: DAPI for nuclear staining.
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