Anti-Matrin 3 Antibody (CAB1027)
- SKU:
- CAB1027
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ALS21
- Synonyms:
- MPD2
- Synonyms:
- VCPDM
- Research Area:
- Immunology
Description
| Product Name: | Matrin 3 Rabbit mAb |
| Product Code: | CAB1027 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ALS21, MPD2, VCPDM |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Matrin 3 |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, K-562, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human Matrin 3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9782 |
| Uniprot: | P43243 |
| Cellular Location: | Nucleus matrix |
| Calculated MW: | 125kDa |
| Observed MW: | 120kDa |
| UniProt Protein Function: | matrin 3: an acidic protein that is a component of the nuclear matrix. May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. |
| UniProt Protein Details: | Protein type:RNA-binding; RNA processing Chromosomal Location of Human Ortholog: 5q31.2 Cellular Component: membrane; nuclear inner membrane; nucleoplasm Molecular Function:protein binding; structural molecule activity Disease: Amyotrophic Lateral Sclerosis 21 |
| NCBI Summary: | This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013] |
| UniProt Code: | P43243 |
| NCBI GenInfo Identifier: | 12643409 |
| NCBI Gene ID: | 9782 |
| NCBI Accession: | P43243.2 |
| UniProt Secondary Accession: | P43243,Q9UHW0, Q9UQ27, B7ZAV5, D3DQC3, |
| UniProt Related Accession: | P43243 |
| Molecular Weight: | 62,576 Da |
| NCBI Full Name: | Matrin-3 |
| NCBI Synonym Full Names: | matrin 3 |
| NCBI Official Symbol: | MATR3 |
| NCBI Official Synonym Symbols: | MPD2; ALS21; VCPDM |
| NCBI Protein Information: | matrin-3 |
| UniProt Protein Name: | Matrin-3 |
| Protein Family: | Matrin |
| UniProt Gene Name: | MATR3 |
| UniProt Entry Name: | MATR3_HUMAN |
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