Description
Product Name: | MAPK4 Rabbit pAb |
Product Code: | CAB8144 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | MAPK4, ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 348-587 of human MAPK4 (NP_002738.2). |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | U-251MG, HeLa |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 348-587 of human MAPK4 (NP_002738.2). |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | SNWD TCSS RYPV SLSS DLEW RPDR CQDA SEVQ RDPR AGSA PLAE DVQV DPRK DSHS SSER FLEQ SHSS MERA FEAD YGRS CDYK VGSP SYLD KLLW RDNK PHHY SEPK LILD LSHW KQAA GAPP TATG LADT GARE DEPA SLFL EIAQ WVKS TQGG PEHA SPPA DDPE RRLS ASPP GRPA PVDG GASP QFDL DVFI SRAL KLCT KPED LPDN KLGD LNGA CIPE HPGD LVQT EAFS KERW |
Gene ID: | 5596 |
Uniprot: | P31152 |
Cellular Location: | Cytoplasm, Nucleus |
Calculated MW: | 65kDa |
Observed MW: | 66kDa |
UniProt Protein Function: | ERK4: a protein kinase of the MAPK family. Phosphorylation and activations leads to translocation into the nucleus where it phosphorylates nuclear targets. Protein type: Protein kinase, CMGC; Kinase, protein; EC 2.7.11.24; Protein kinase, Ser/Thr (non-receptor); CMGC group; MAPK family; MAPK/ERK subfamily; ERK subfamily Chromosomal Location of Human Ortholog: 18q21.1 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function: protein binding; protein homodimerization activity; protein kinase binding; protein serine/threonine kinase activity Biological Process: protein amino acid phosphorylation |
UniProt Protein Details: | |
NCBI Summary: | Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
UniProt Code: | P31152 |
NCBI GenInfo Identifier: | 215274102 |
NCBI Gene ID: | 5596 |
NCBI Accession: | P31152.2 |
UniProt Secondary Accession: | P31152,Q0VG04, A1A4C4 |
UniProt Related Accession: | P31152 |
Molecular Weight: | 65,922 Da |
NCBI Full Name: | Mitogen-activated protein kinase 4 |
NCBI Synonym Full Names: | mitogen-activated protein kinase 4 |
NCBI Official Symbol: | MAPK4 |
NCBI Official Synonym Symbols: | ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK |
NCBI Protein Information: | mitogen-activated protein kinase 4 |
UniProt Protein Name: | Mitogen-activated protein kinase 4 |
UniProt Synonym Protein Names: | Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK |
Protein Family: | |
UniProt Gene Name: | MAPK4 |
UniProt Entry Name: | MK04_HUMAN |