| UniProt Protein Function: | ERK4: a protein kinase of the MAPK family. Phosphorylation and activations leads to translocation into the nucleus where it phosphorylates nuclear targets. Protein type: Protein kinase, CMGC; Kinase, protein; EC 2.7.11.24; Protein kinase, Ser/Thr (non-receptor); CMGC group; MAPK family; MAPK/ERK subfamily; ERK subfamily Chromosomal Location of Human Ortholog: 18q21.1 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function: protein binding; protein homodimerization activity; protein kinase binding; protein serine/threonine kinase activity Biological Process: protein amino acid phosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| UniProt Code: | P31152 |
| NCBI GenInfo Identifier: | 215274102 |
| NCBI Gene ID: | 5596 |
| NCBI Accession: | P31152.2 |
| UniProt Secondary Accession: | P31152,Q0VG04, A1A4C4 |
| UniProt Related Accession: | P31152 |
| Molecular Weight: | 65,922 Da |
| NCBI Full Name: | Mitogen-activated protein kinase 4 |
| NCBI Synonym Full Names: | mitogen-activated protein kinase 4 |
| NCBI Official Symbol: | MAPK4 |
| NCBI Official Synonym Symbols: | ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK |
| NCBI Protein Information: | mitogen-activated protein kinase 4 |
| UniProt Protein Name: | Mitogen-activated protein kinase 4 |
| UniProt Synonym Protein Names: | Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK |
| Protein Family: | |
| UniProt Gene Name: | MAPK4 |
| UniProt Entry Name: | MK04_HUMAN |