Cell Biology Antibodies 1

MEK1 Rabbit Polyclonal Antibody (CAB0252)

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SKU:
CAB0252
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
MEL, CFC3, MEK1, MKK1, MAPKK1, PRKMK1
Research Use:
Cell Biology
Frequently bought together:

Description

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MEK1 Antibody (CAB0252)

The MEK1 Antibody (CAB0252) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it an excellent choice for Western blot applications.MAP2K1, also known as MEK1, is a critical component of the MAPK/ERK pathway, which is involved in regulating various cellular processes such as cell cycle progression and survival.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MEK1 Antibody
SKU:CAB0252
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MPKK KPTP IQLN PAPD GSAV NGTS SAET NLEA LQKK LEEL ELDE QQRK RLEA FLTQ KQKV GELK DDDF EKIS ELGA GNGG VVFK VSHK PSGL VMAR KLIH
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MEL, CFC3, MEK1, MKK1, MAPKK1, PRKMK1
Positive Sample:Mouse lung, Mouse stomach, Mouse brain
Cellular Localization:Cytoplasm, Membrane, Nucleus, Peripheral Membrane Protein, Centrosome, Cytoskeleton, Microtubule Organizing Center, Spindle Pole Body.
Calculated MW:43kDa
Observed MW:46kDa

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Purification MethodAffinity purification
Gene ID5604
RRIDAB_2757065
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MEK1 Rabbit pAb (CAB0252). Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product ImageImmunofluorescence analysis of U2OS cells using MEK1 Rabbit pAb (CAB0252). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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