Cell Biology Antibodies 16
Anti-Mannose Receptor/CD206 Antibody (CAB11192)
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- SKU:
- CAB11192
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Mannose Receptor/CD206 Antibody |
| Antibody SKU: | CAB11192 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Mannose Receptor/CD206 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Raji, Mouse lung |
| Immunogen: | A synthesized peptide derived from human Mannose Receptor/CD206 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4360 |
| Uniprot: | P22897 |
| Cellular Location: | |
| Calculated MW: | 166kDa |
| Observed MW: | 166KDa |
 | Western blot - Mannose Receptor/CD206 Rabbit mAb (CAB11192) |
| Synonyms: | CD206, CLEC13D, CLEC13DL, MMR, MRC1L1, bA541I19.1, hMR |
| Background: | The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015] |
| UniProt Protein Function: | MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc. Chromosomal Location of Human Ortholog: 10p12.33 Cellular Component: endosome membrane; integral to plasma membrane; plasma membrane Molecular Function:protein binding; receptor activity; transmembrane receptor activity Biological Process: receptor-mediated endocytosis |
| NCBI Summary: | The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015] |
| UniProt Code: | P22897 |
| NCBI GenInfo Identifier: | 126730 |
| NCBI Gene ID: | 4360 |
| NCBI Accession: | P22897.1 |
| UniProt Secondary Accession: | P22897,Q5VSJ2, Q5VSK2, A5PKW3, |
| UniProt Related Accession: | P22897 |
| Molecular Weight: | 166kDa |
| NCBI Full Name: | Macrophage mannose receptor 1 |
| NCBI Synonym Full Names: | mannose receptor C-type 1 |
| NCBI Official Symbol: | MRC1 |
| NCBI Official Synonym Symbols: | MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1 |
| NCBI Protein Information: | macrophage mannose receptor 1 |
| UniProt Protein Name: | Macrophage mannose receptor 1 |
| UniProt Synonym Protein Names: | C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human mannose receptor; hMR; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206 |
| Protein Family: | Macrophage mannose receptor |
| UniProt Gene Name: | MRC1 |
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