Cell Biology Antibodies 14

Anti-LUC7L3 Antibody (CAB18104)

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SKU:
CAB18104
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-LUC7L3 Antibody
Antibody SKU:CAB18104
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-200 of human LUC7L3 (NP_057508.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-200 of human LUC7L3 (NP_057508.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KIHD ENLR KQYE KSSR FMKV GYER DFLR YLQS LLAE VERR IRRG HARL ALSQ NQQS SGAA GPTG KNEE KIQV LTDK IDVL LQQI EELG SEGK VEEA QGMM KLVE QLKE EREL LRST TSTI ESFA AQEK QMEV CEVC GAFL I
Gene ID:51747
Uniprot:O95232
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:CRA, CREAP-1, CROP, LUC7A, OA48-18, hLuc7A, LUC7L3
Background:
UniProt Protein Function:CROP: Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. Belongs to the Luc7 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Spliceosome; DNA-binding; RNA-binding

Chromosomal Location of Human Ortholog: 17q21.33

Cellular Component: nucleoplasm; nuclear speck; snRNP U1; nucleus

Molecular Function:mRNA binding; protein binding; DNA binding

Biological Process: mRNA splice site selection; RNA splicing

NCBI Summary:This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009]
UniProt Code:O95232
NCBI GenInfo Identifier:33990586
NCBI Gene ID:51747
NCBI Accession:AAH56409.1
UniProt Secondary Accession:O95232,Q6PHR9, Q9NUY0, Q9P2S7, B3KN54, D3DTY1,
UniProt Related Accession:O95232
Molecular Weight:9,194 Da
NCBI Full Name:CROP protein
NCBI Synonym Full Names:LUC7-like 3 (S. cerevisiae)
NCBI Official Symbol:LUC7L3  
NCBI Official Synonym Symbols:CRA; CROP; LUC7A; hLuc7A; CREAP-1; OA48-18  
NCBI Protein Information:luc7-like protein 3; CRE-associated protein 1; cAMP regulatory element-associated protein 1; cisplatin resistance associated overexpressed protein; cisplatin resistance-associated overexpressed protein; cisplatin resistance-associated-overexpressed protein; okadaic acid-inducible phosphoprotein OA48-18
UniProt Protein Name:Luc7-like protein 3
UniProt Synonym Protein Names:Cisplatin resistance-associated-overexpressed protein; Luc7A; Okadaic acid-inducible phosphoprotein OA48-18; cAMP regulatory element-associated protein 1; CRE-associated protein 1; CREAP-1
Protein Family:Luc7-like protein
UniProt Gene Name:LUC7L3  
UniProt Entry Name:LC7L3_HUMAN
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