Anti-LRP1 Antibody

LRP1 Antibody

LRP1 Antibody is a rabbit polyclonal antibody directed against LRP1, offered by Assay Genie for research applications. Reported applications include WB and IHC. Reported reactivity: Human, Mouse and Rat. Purified by Peptide Affinity.

LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) is a multifunctional endocytic receptor involved in lipid metabolism, protease clearance, and cell signaling. In the brain, LRP1 regulates amyloid-beta clearance, synaptic plasticity, and blood-brain barrier integrity. Dysregulation of LRP1 is associated with Alzheimer’s disease, where impaired Aβ clearance contributes to plaque accumulation and neurotoxicity. LRP1 also modulates neuroinflammatory responses and interacts with key signaling pathways, including Wnt and TGF-β. Its broad functional repertoire and role in maintaining neural homeostasis make LRP1 a critical target in neurodegenerative disease research and therapeutic development. This antibody is also available conjugated to ATTO 390, ATTO 488, ATTO 594, APC, Biotin, FITC, HRP, PerCP and RPE. Supplied in 100 µg. For research use only; not for diagnostic or therapeutic procedures.