Lipin 1 Rabbit Monoclonal Antibody (CAB3326)

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SKU:
CAB3326
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
Reactivity:
Human, Mouse, Rat
Synonyms:
PAP1, Lipin 1
Research Use:
Metabolism
Frequently bought together:

Description

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Lipin 1 Monoclonal Antibody (CAB3326)

The Lipin 1 Monoclonal Antibody (CAB3326) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, is highly specific to Lipin 1 and is validated for use in Western blot applications. By binding specifically to Lipin 1 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for studies in metabolic disorders, obesity, and lipid-related diseases.Lipin 1 is a critical enzyme that plays a crucial role in lipid metabolism, including triglyceride synthesis and phospholipid biosynthesis.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Lipin 1 Monoclonal Antibody
SKU:CAB3326
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Clone Number:ARC1945
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MHLA TSPI LSEG ASRM ECQL KRGS VDRM RGLD PSTP AQVI APSE TPSS SSVV KKRR KRRR KSQL DSLK RDDN MNTS EDED MFPI EMSS DEAM ELLE SSRT
Tested Applications:WB ELISA
Recommended Dilution:
WB1:1000 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PAP1, Lipin 1
Positive Sample:HeLa, Hep G2, NIH/3T3, RD, Mouse testis, Rat testis
Cellular Localization:Cytoplasm, Endoplasmic Reticulum Membrane, Nucleus Membrane, Cytosol.
Calculated MW:99kDa
Observed MW:130kDa

This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes.

Purification MethodAffinity purification
Gene ID23175
RRIDAB_2863039
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Lipin 1 Rabbit mAb (CAB3326) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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