Developmental Biology

Anti-LHFPL2 Antibody (CAB12808)

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SKU:
CAB12808
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-LHFPL2 Antibody
Antibody SKU:CAB12808
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human LHFPL2 (NP_005770.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human
Positive Samples:K-562
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human LHFPL2 (NP_005770.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SADW LIGK ARSR GGVE PAGP GGGS PEPY HPTL GIYA RCIR NPGV QHFQ RDTL CGPY AESF GEIA SGFW QAT
Gene ID:10184
Uniprot:Q6ZUX7
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:24kDa
Observed MW:26kDa
Synonyms:LHFPL2
Background:This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
UniProt Protein Function:LHFPL2: a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q14.1

Cellular Component: plasma membrane; platelet alpha granule membrane

Biological Process: platelet degranulation

NCBI Summary:This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q6ZUX7
NCBI GenInfo Identifier:116242618
NCBI Gene ID:10184
NCBI Accession:Q6ZUX7.2
UniProt Secondary Accession:Q6ZUX7,Q7Z5P0, Q92605, B2RMQ6,
UniProt Related Accession:Q6ZUX7
Molecular Weight:24kDa
NCBI Full Name:Lipoma HMGIC fusion partner-like 2 protein
NCBI Synonym Full Names:lipoma HMGIC fusion partner-like 2
NCBI Official Symbol:LHFPL2  
NCBI Protein Information:lipoma HMGIC fusion partner-like 2 protein
UniProt Protein Name:Lipoma HMGIC fusion partner-like 2 protein
Protein Family:Lipoma HMGIC fusion partner-like 2 protein
UniProt Gene Name:LHFPL2  
Anti-LHFPL2 Antibody (CAB12808)Western blot analysis of extracts of K-562 cells, using LHFPL2 antibody (CAB12808) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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