Signal Transduction Antibodies 1

Anti-KCNG4 Antibody (CAB14435)

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SKU:
CAB14435
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-KCNG4 Antibody
Antibody SKU:CAB14435
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human KCNG4 (NP_758857.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, DU145, 293T, Mouse testis, Mouse eye, Mouse brain, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human KCNG4 (NP_758857.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPMP SRDG GLHP RHHH YGSH SPWS QLLS SPME TPSI KGLY YRRV RKVG ALDA SPVD LKKE ILIN VGGR RYLL PWST LDRF PLSR LSKL RLCR SYEE IVQL CDDY DEDS QEFF FDRS PSAF GVIV SFLA AGKL VLLQ EMCA LSFQ EELA YWGI EEAH LERC CLRK LLRK LEEL EELA KLHR EDVL RQQR ETRR PASH SSRW GLCM NRLR EMVE NPQS GLPG
Gene ID:93107
Uniprot:Q8TDN1
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:29kDa/58kDa
Observed MW:59kDa
Synonyms:KCNG4, KV6.3, KV6.4
Background:Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues.
UniProt Code:Q8TDN1
NCBI GenInfo Identifier:649145154
NCBI Gene ID:
NCBI Accession:NP_758857
Molecular Weight:59kDa
NCBI Full Name:KCNG4, partial
UniProt Protein Name:
Protein Family:Potassium voltage-gated channel subfamily
UniProt Gene Name:
Anti-KCNG4 Antibody (CAB14435)Western blot analysis of extracts of various cell lines, using KCNG4 antibody (CAB14435) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s.
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