Signal Transduction Antibodies 1
Anti-KCNAB3 Antibody (CAB14822)
- SKU:
- CAB14822
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Antibody Name: | Anti-KCNAB3 Antibody |
Antibody SKU: | CAB14822 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human KCNAB3 (NP_004723.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse brain, Mouse heart, Rat brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human KCNAB3 (NP_004723.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | YPLA CGLI TSKY DGRV PDTC RASI KGYQ WLKD KVQS EDGK KQQA KVMD LLPV AHQL GCTV AQLA IAWC LRSE GVSS VLLG VSSA EQLI EHLG ALQV LSQL TPQT VMEI DGLL GNKP HSKK |
Gene ID: | 9196 |
Uniprot: | O43448 |
Cellular Location: | Cytoplasm |
Calculated MW: | 43kDa |
Observed MW: | 44kDa |
Synonyms: | KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3 |
Background: | This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit. |
UniProt Protein Function: | KCNAB3: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5. Belongs to the shaker potassium channel beta subunit family. |
UniProt Protein Details: | Protein type:Channel, potassium Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: plasma membrane Molecular Function:potassium channel regulator activity Biological Process: potassium ion transport |
NCBI Summary: | This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit. [provided by RefSeq, May 2012] |
UniProt Code: | O43448 |
NCBI GenInfo Identifier: | 126302560 |
NCBI Gene ID: | 9196 |
NCBI Accession: | O43448.2 |
UniProt Secondary Accession: | O43448,Q4VAW0, |
UniProt Related Accession: | O43448 |
Molecular Weight: | 43,670 Da |
NCBI Full Name: | Voltage-gated potassium channel subunit beta-3 |
NCBI Synonym Full Names: | potassium voltage-gated channel subfamily A regulatory beta subunit 3 |
NCBI Official Symbol: | KCNAB3 |
NCBI Official Synonym Symbols: | AKR6A9; KCNA3B; KCNA3.1B; KV-BETA-3 |
NCBI Protein Information: | voltage-gated potassium channel subunit beta-3 |
UniProt Protein Name: | Voltage-gated potassium channel subunit beta-3 |
UniProt Synonym Protein Names: | K(+) channel subunit beta-3; Kv-beta-3 |
Protein Family: | Voltage-gated potassium channel |
UniProt Gene Name: | KCNAB3 |
UniProt Entry Name: | KCAB3_HUMAN |
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