Signal Transduction Antibodies 1

Anti-KCNAB3 Antibody (CAB14821)

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SKU:
CAB14821
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-KCNAB3 Antibody
Antibody SKU:CAB14821
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human KCNAB3 (NP_004723.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse brain, Mouse kidney, Mouse lung, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human KCNAB3 (NP_004723.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:YPLA CGLI TSKY DGRV PDTC RASI KGYQ WLKD KVQS EDGK KQQA KVMD LLPV AHQL GCTV AQLA IAWC LRSE GVSS VLLG VSSA EQLI EHLG ALQV LSQL TPQT VMEI DGLL GNKP HSKK
Gene ID:9196
Uniprot:O43448
Cellular Location:Cytoplasm
Calculated MW:43kDa
Observed MW:44kDa
Synonyms:KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3
Background:This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit.
UniProt Protein Function:KCNAB3: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5. Belongs to the shaker potassium channel beta subunit family.
UniProt Protein Details:

Protein type:Channel, potassium

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: plasma membrane

Molecular Function:potassium channel regulator activity

Biological Process: potassium ion transport

NCBI Summary:This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit. [provided by RefSeq, May 2012]
UniProt Code:O43448
NCBI GenInfo Identifier:126302560
NCBI Gene ID:9196
NCBI Accession:O43448.2
UniProt Secondary Accession:O43448,Q4VAW0,
UniProt Related Accession:O43448
Molecular Weight:43,670 Da
NCBI Full Name:Voltage-gated potassium channel subunit beta-3
NCBI Synonym Full Names:potassium voltage-gated channel subfamily A regulatory beta subunit 3
NCBI Official Symbol:KCNAB3  
NCBI Official Synonym Symbols:AKR6A9; KCNA3B; KCNA3.1B; KV-BETA-3  
NCBI Protein Information:voltage-gated potassium channel subunit beta-3
UniProt Protein Name:Voltage-gated potassium channel subunit beta-3
UniProt Synonym Protein Names:K(+) channel subunit beta-3; Kv-beta-3
Protein Family:Voltage-gated potassium channel
UniProt Gene Name:KCNAB3  
UniProt Entry Name:KCAB3_HUMAN
Anti-KCNAB3 Antibody (CAB14821)Western blot analysis of extracts of various cell lines, using KCNAB3 antibody (CAB14821) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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