Description
| Antibody Name: | Anti-ITPA Antibody (CAB9370) | 
| Antibody SKU: | CAB9370 | 
| Antibody Size: | 50µL, 100µL | 
| Application: | Western blotting | 
| Reactivity: | Human, Mouse | 
| Host Species: | Rabbit | 
| Immunogen: | A synthesized peptide derived from human ITPA. | 
| Application: | Western blotting | 
| Recommended Dilution: | WB 1:500 - 1:2000 | 
| Reactivity: | Human, Mouse | 
| Positive Samples: | HT-29, HepG2, Mouse kidney | 
| Immunogen: | A synthesized peptide derived from human ITPA. | 
| Purification Method: | Affinity purification | 
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.  | 
| Isotype: | IgG | 
| Sequence: | Email for sequence | 
| Cellular Location: | Cytoplasm | 
| Calculated MW: | 22kDa | 
| Observed MW: | 21KDa | 
| Synonyms: | ITPA, C20orf37, HLC14-06-P, ITPase, My049, NTPase, dJ794I6.3, inosine triphosphatase | 
| Background: | This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants. | 
![]()  | Western blot analysis of extracts of various cell lines, using at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s. | 
            