Cell Biology Antibodies 4

Anti-ITGA9 Antibody (CAB14007)

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SKU:
CAB14007
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ITGA9 Antibody
Antibody SKU:CAB14007
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-250 of human ITGA9 (NP_002198.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:NIH/3T3, A673
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-250 of human ITGA9 (NP_002198.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:YNLD PQRP VHFQ GPAD SFFG YAVL EHFH DNTR WVLV GAPK ADSK YSPS VKSP GAVF KCRV HTNP DRRC TELD MARG KNRG TSCG KTCR EDRD DEWM GVSL ARQP KADG RVLA CAHR WKNI YYEA DHIL PHGF CYII PSNL QAKG RTLI PCYE EYKK KYGE EHGS CQAG IAGF FTEE LVVM GAPG SFYW AGTI KVLN LTDN TYLK LNDE VIMN RRYT YLGY A
Gene ID:3680
Uniprot:Q13797
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:114kDa
Observed MW:114kDa
Synonyms:ITGA9, ALPHA-RLC, ITGA4L, RLC
Background:This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
UniProt Protein Function:ITGA9: Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin. Belongs to the integrin alpha chain family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: basal plasma membrane; plasma membrane; integrin complex

Molecular Function:collagen binding; metal ion binding; laminin binding

Biological Process: integrin-mediated signaling pathway; neutrophil chemotaxis; axon guidance; extracellular matrix organization and biogenesis; wound healing; cell adhesion

NCBI Summary:This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]
UniProt Code:Q13797
NCBI GenInfo Identifier:229462922
NCBI Gene ID:3680
NCBI Accession:Q13797.2
UniProt Related Accession:Q13797
Molecular Weight:
NCBI Full Name:Integrin alpha-9
NCBI Synonym Full Names:integrin subunit alpha 9
NCBI Official Symbol:ITGA9  
NCBI Official Synonym Symbols:RLC; ITGA4L; ALPHA-RLC  
NCBI Protein Information:integrin alpha-9
UniProt Protein Name:Integrin alpha-9
UniProt Synonym Protein Names:Integrin alpha-RLC
UniProt Gene Name:ITGA9  
UniProt Entry Name:ITA9_HUMAN
Anti-ITGA9 Antibody (CAB14007)Western blot analysis of extracts of various cell lines, using ITGA9 antibody (CAB14007) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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