Anti-IRAK4 Antibody (CAB20839)

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SKU:
CAB20839
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG

Description

Antibody Name:Anti-IRAK4 Antibody (CAB20839)
Antibody SKU:CAB20839
Antibody Size:50µL, 100µL
Application:Western blotting
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IRAK4 (NP_057207.2).
Application:Western blotting
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:Jurkat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IRAK4 (NP_057207.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MNKP ITPS TYVR CLNV GLIR KLSD FIDP QEGW KKLA VAIK KPSG DDRY NQFH IRRF EALL QTGK SPTS ELLF DWGT TNCT VGDL VDLL IQNE FFAP ASLL LPDA VPKT ANTL PSKE AITV QQKQ MPFC DKDR TLMT PVQN LEQS YMPP DSSS PENK SLEV SDTR FHSF SFYE LKNV TNNF DERP ISVG GNKM GEGG FGVV
Cellular Location:Cytoplasm
Calculated MW:37kDa/51kDa
Observed MW:55KDa
Synonyms:IRAK4, IPD1, IRAK-4, NY-REN-64, REN64
Background:This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Western blot analysis of extracts of Jurkat cells, using IRAK4 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 45s.Western blot analysis of extracts of Jurkat cells, using IRAK4 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 45s.
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