Anti-Involucrin Antibody (CAB13311)
- SKU:
- CAB13311
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Product Name: | Involucrin Rabbit mAb |
| Product Code: | CAB13311 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Involucrin |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Rat lung |
| Immunogen: | A synthesized peptide derived from human Involucrin |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3713 |
| Uniprot: | P07476 |
| Calculated MW: | 120kDa |
| Observed MW: | 90KDa |
| UniProt Protein Function: | IVL: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. Belongs to the involucrin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; cornified envelope Molecular Function:protein binding, bridging; structural molecule activity Biological Process: keratinocyte differentiation; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; keratinization; peptide cross-linking; response to UV-B |
| NCBI Summary: | Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P07476 |
| NCBI GenInfo Identifier: | 254763301 |
| NCBI Gene ID: | 3713 |
| NCBI Accession: | P07476.2 |
| UniProt Secondary Accession: | P07476,Q5T7P4, |
| UniProt Related Accession: | P07476 |
| Molecular Weight: | 68,479 Da |
| NCBI Full Name: | Involucrin |
| NCBI Synonym Full Names: | involucrin |
| NCBI Official Symbol: | IVL |
| NCBI Protein Information: | involucrin |
| UniProt Protein Name: | Involucrin |
| Protein Family: | Involucrin |
| UniProt Gene Name: | IVL |
| UniProt Entry Name: | INVO_HUMAN |
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