Cell Biology Antibodies 17

Integrin linked ILK Rabbit Monoclonal Antibody (CAB4571)

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SKU:
CAB4571
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
P59, ILK-1, ILK-2, p59ILK, HEL-S-28, Integrin linked ILK
Research Use:
Cell Biology
Frequently bought together:

Description

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Integrin linked ILK Monoclonal Antibody (CAB4571)

The Integrin linked ILK Monoclonal Antibody (CAB4571) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards ILK in human samples, making it ideal for Western blot applications.ILK is a multifunctional protein that plays a crucial role in cell adhesion, migration, and survival. It is involved in various cellular processes, including cytoskeletal organization, gene expression, and cell proliferation.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Integrin linked ILK Monoclonal Antibody
SKU:CAB4571
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Clone Number:ARC1037
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MYAP AWVA PEAL QKKP EDTN RRSA DMWS FAVL LWEL VTRE VPFA DLSN MEIG MKVA LEGL RPTI PPGI SPHV CKLM KICM NEDP AKRP KFDM IVPI LEKM QDK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:P59, ILK-1, ILK-2, p59ILK, HEL-S-28, Integrin linked ILK
Positive Sample:HT-29, Raji, Mouse spleen, Mouse kidney, Rat lung, Rat spleen, Rat kidney
Cellular Localization:Cell Junction, Cell Membrane, Cell Projection, Cytoplasm, Cytoplasmic Side, Peripheral Membrane Protein, Focal Adhesion, Lamellipodium, Myofibril, Sarcomere.
Calculated MW:51kDa
Observed MW:49kDa

This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID3611
RRIDAB_2863299
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Integrin linked ILK Rabbit mAb (CAB4571) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageWestern blot analysis of various lysates using Integrin linked ILK Rabbit mAb (CAB4571) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
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