Signal Transduction Antibodies 1
Anti-INSL4 Antibody (CAB13025)
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- SKU:
- CAB13025
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-INSL4 Antibody |
| Antibody SKU: | CAB13025 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-139 of human INSL4 (NP_002186.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-139 of human INSL4 (NP_002186.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASL FRSY LPAI WLLL SQLL RESL AAEL RGCG PRFG KHLL SYCP MPEK TFTT TPGG WLLE SGRP KEMV STSN NKDG QALG TTSE FIPN LSPE LKKP LSEG QPSL KKII LSRK KRSG RHRF DPFC CEVI CDDG TSVK LCT |
| Gene ID: | 3641 |
| Uniprot: | Q14641 |
| Cellular Location: | Secreted |
| Calculated MW: | 15kDa |
| Observed MW: | 12kDa |
| Synonyms: | INSL4, EPIL, PLACENTIN |
| Background: | INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast. |
| UniProt Protein Function: | INSL4: May play an important role in trophoblast development and in the regulation of bone formation. Belongs to the insulin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9p24 Cellular Component: extracellular space Molecular Function:insulin-like growth factor receptor binding; hormone activity; receptor binding Biological Process: cell proliferation; cell-cell signaling; multicellular organismal development; female pregnancy; signal transduction |
| NCBI Summary: | INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14641 |
| NCBI GenInfo Identifier: | 119579176 |
| NCBI Gene ID: | 3641 |
| NCBI Accession: | EAW58772.1 |
| UniProt Secondary Accession: | Q14641,Q5W127, A8K678, |
| UniProt Related Accession: | Q14641 |
| Molecular Weight: | 15,445 Da |
| NCBI Full Name: | insulin-like 4 (placenta) |
| NCBI Synonym Full Names: | insulin-like 4 (placenta) |
| NCBI Official Symbol: | INSL4 |
| NCBI Official Synonym Symbols: | EPIL; PLACENTIN |
| NCBI Protein Information: | early placenta insulin-like peptide |
| UniProt Protein Name: | Early placenta insulin-like peptide |
| UniProt Synonym Protein Names: | Insulin-like peptide 4; Placentin |
| Protein Family: | Early placenta insulin-like peptide |
| UniProt Gene Name: | INSL4 |
| UniProt Entry Name: | INSL4_HUMAN |
 | Western blot analysis of extracts of rat lung, using INSL4 antibody (CAB13025) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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