Anti-IL1RN Antibody (CAB21089)
- SKU:
- CAB21089
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Anti-IL1RN Antibody (CAB21089) |
| Antibody SKU: | CAB21089 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting, Immunofluorescence |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-178 of mouse IL1RN (NP_001034790.1). |
| Application: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-431, PC-3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-178 of mouse IL1RN (NP_001034790.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RPSG KRPC KMQA FRIW DTNQ KTFY LRNN QLIA GYLQ GPNI KLEE KIDM VPID LHSV FLGI HGGK LCLS CAKS GDDI KLQL EEVN ITDL SKNK EEDK RFTF IRSE KGPT TSFE SAAC PGWF LCTT LEAD RPVS LTNT PEEP LIVT KFYF QEDQ |
| Cellular Location: | |
| Calculated MW: | 20kDa |
| Observed MW: | 18KDa |
| Synonyms: | IL-1ra, F630041P17Rik |
| Background: | Predicted to enable cytokine receptor binding activity. Acts upstream of or within insulin secretion and lipid metabolic process. Located in extracellular region and vesicle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human IL1RN (interleukin 1 receptor antagonist). |
 | Immunofluorescence analysis of NIH/3T3 cells using IL1RN Rabbit pAb at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining. |
 | Western blot analysis of extracts of various cell lines, using IL1RN antibody at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s. |
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