Anti-IL-6 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0263)
- SKU:
- HDAB0263
- Product Type:
- Rabbit Monoclonal Antibody
- Antibody Type:
- Monoclonal Antibody
- Size:
- 100 μg
- Reactivity:
- Human
- Host Species:
- Rabbit
- Antibody Isotype:
- Rabbit/Human Fc chimeric IgG1
- Clone:
- DMC419
- Synonyms:
- IL6, Interleukin-6, BSF2, HSF, IFNB2
Description
system_update_altDatasheet
SKU: | HDAB0263 |
Size: | 100 µg |
Clonality: | Monoclonal |
Clone: | DMC419 |
Synonyms: | IL6, Interleukin-6, BSF2, HSF, IFNB2 |
Applications: | Flow Cyt |
Recommended Dilution: | Flow Cyt 1:100 |
Host Species: | Rabbit |
Isotype: | Rabbit/Human Fc chimeric IgG1 |
Reactivity: | Human |
Purification Method: | Purified from cell culture supernatant by affinity chromatography |
Formulation: | Powder |
Buffer: | 1XPBS |
Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
Usage: | Research use only |
Background: | This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. |