Cell Biology Antibodies 1

Anti-IL-20RA Antibody (CAB10308)

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SKU:
CAB10308
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:IL20RA Rabbit Polyclonal Antibody
Antibody SKU:CAB10308
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human IL20RA
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:MCF7, U-87MG, A375, SW620, Mouse liver
Immunogen:Recombinant protein of human IL20RA
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:53832
Uniprot:Q9UHF4
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:49kDa/57kDa/62kDa
Observed MW:75kDa
Synonyms:IL20RA, CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA
Background:This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:IL20RA: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. Belongs to the type II cytokine receptor family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q23.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway

NCBI Summary:This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UniProt Code:Q9UHF4
NCBI GenInfo Identifier:145559483
NCBI Gene ID:53832
NCBI Accession:Q9UHF4.2
UniProt Secondary Accession:Q9UHF4,Q14CW2, Q6UWA9, Q96SH8, B4DLR5, F5H675,
UniProt Related Accession:Q9UHF4
Molecular Weight:62kDa
NCBI Full Name:Interleukin-20 receptor subunit alpha
NCBI Synonym Full Names:interleukin 20 receptor subunit alpha
NCBI Official Symbol:IL20RA  
NCBI Official Synonym Symbols:CRF2-8; IL-20R1; IL-20RA; IL-20R-alpha  
NCBI Protein Information:interleukin-20 receptor subunit alpha
UniProt Protein Name:Interleukin-20 receptor subunit alpha
UniProt Synonym Protein Names:Cytokine receptor class-II member 8; Cytokine receptor family 2 member 8; CRF2-8; IL-20R1; ZcytoR7
Protein Family:Interleukin-20 receptor
UniProt Gene Name:IL20RA  
Anti-IL-20RA Antibody (CAB10308)Western blot analysis of extracts of various cell lines, using IL20RA antibody (CAB10308) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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