Cell Biology Antibodies 14
Anti-HOXB4 Antibody (CAB16878)
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- SKU:
- CAB16878
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-HOXB4 Antibody |
| Antibody SKU: | CAB16878 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB4 (NP_076920.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HL-60, Mouse liver |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB4 (NP_076920.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PEAG FGRR AACT VQRY AACR DPGP PPPP PPPP PPPP PPGL SPRA PAPP PAGA LLPE PGQR CEAV SSSP PPPP CAQN PLHP SPSH SACK EPVV YPWM RKVH V |
| Gene ID: | 3214 |
| Uniprot: | P17483 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 38kDa |
 | Western blot - HOXB4 Rabbit pAb (CAB16878) |
| Synonyms: | HOXB4, HOX-2.6, HOX2, HOX2F |
| Background: | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. |
| UniProt Protein Function: | HOXB4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Deformed subfamily. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 17q21.32 Biological Process: positive regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P17483 |
| NCBI GenInfo Identifier: | 547692 |
| NCBI Gene ID: | 3214 |
| NCBI Accession: | P17483.2 |
| UniProt Secondary Accession: | P17483,Q9NTA0, |
| UniProt Related Accession: | P17483 |
| Molecular Weight: | 27,604 Da |
| NCBI Full Name: | Homeobox protein Hox-B4 |
| NCBI Synonym Full Names: | homeobox B4 |
| NCBI Official Symbol: | HOXB4 |
| NCBI Official Synonym Symbols: | HOX2; HOX2F; HOX-2.6 |
| NCBI Protein Information: | homeobox protein Hox-B4 |
| UniProt Protein Name: | Homeobox protein Hox-B4 |
| UniProt Synonym Protein Names: | Homeobox protein Hox-2.6; Homeobox protein Hox-2F |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | HOXB4 |
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