UniProt Protein Function: | Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. |
NCBI Summary: | This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016] |
UniProt Code: | P51858 |
NCBI GenInfo Identifier: | 1708157 |
NCBI Gene ID: | 3068 |
NCBI Accession: | P51858.1 |
UniProt Secondary Accession: | P51858,Q5SZ07, Q5SZ08, Q5SZ09, B3KU21, D3DVC9, |
UniProt Related Accession: | P51858 |
Molecular Weight: | 28,264 Da |
NCBI Full Name: | Hepatoma-derived growth factor |
NCBI Synonym Full Names: | hepatoma-derived growth factor |
NCBI Official Symbol: | HDGF |
NCBI Official Synonym Symbols: | HMG1L2 |
NCBI Protein Information: | hepatoma-derived growth factor |
UniProt Protein Name: | Hepatoma-derived growth factor |
UniProt Synonym Protein Names: | High mobility group protein 1-like 2; HMG-1L2 |
Protein Family: | Hepatoma-derived growth factor |
UniProt Gene Name: | HDGF |
UniProt Entry Name: | HDGF_HUMAN |