Cell Biology Antibodies 2

Glycophorin C (GYPC) Rabbit Polyclonal Antibody (CAB1232)

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SKU:
CAB1232
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
GE, GPC, GPD, GYPD, CD236, PAS-2, CD236R, PAS-2', Glycophorin C (GYPC)
Research Use:
Cell Biology
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Description

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Glycophorin C (GYPC) Antibody (CAB1232)

The Glycophorin C (GYPC) Antibody (CAB1232) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for detecting Glycophorin-C in human samples, making it an essential reagent for Western blot analysis.Glycophorin-C, a glycoprotein found on the surface of red blood cells, plays a crucial role in maintaining cell shape and stability, as well as mediating cell-cell interactions. Dysregulation of Glycophorin-C expression has been linked to various blood disorders and conditions, making it a target of interest for researchers in hematology and related fields.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:Glycophorin C (GYPC) Antibody
SKU:CAB1232
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MWST RSPN STAW PLSL EPDP GMAS ASTT MHTT TIAE PDPG MSGW PDGR METS TPTI MDIV VIAG VIAA VAIV LVSL LFVM LRYM YRHK GTYH TNEA KGTE FAES ADAA LQGD PALQ DAGD SSRK EYFI
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GE, GPC, GPD, GYPD, CD236, PAS-2, CD236R, PAS-2', Glycophorin C (GYPC)
Positive Sample:HepG2, HL-60, Mouse heart
Cellular Localization:Cell Membrane, Single-Pass Type Iii Membrane Protein.
Calculated MW:14kDa
Observed MW:34kDa

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID2995
RRIDAB_2759172
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Glycophorin C (GYPC) Rabbit pAb (CAB1232) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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