Cell Biology Antibodies 6

Anti-GPR139 Antibody (CAB15946)

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SKU:
CAB15946
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GPR139 Antibody
Antibody SKU:CAB15946
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human GPR139
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HeLa, Mouse brain
Immunogen:Recombinant protein of human GPR139
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:124274
Uniprot:Q6DWJ6
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:40kDa
Observed MW:45kDa
Synonyms:GPR139, GPRg1, PGR3
Background:This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:GPR139: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p12.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function:protein dimerization activity; neuropeptide receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)

UniProt Code:Q6DWJ6
NCBI GenInfo Identifier:50897278
NCBI Gene ID:124274
NCBI Accession:NP_001002911.1
UniProt Secondary Accession:Q6DWJ6,Q86SP2, Q8TDU8, A8K5R9,
UniProt Related Accession:Q6DWJ6
Molecular Weight:40,679 Da
NCBI Full Name:probable G-protein coupled receptor 139
NCBI Synonym Full Names:G protein-coupled receptor 139
NCBI Official Symbol:GPR139  
NCBI Official Synonym Symbols:PGR3; GPRg1  
NCBI Protein Information:probable G-protein coupled receptor 139; G protein-coupled receptor PGR3; G-protein-coupled receptor PGR3; g(q)-coupled orphan receptor GPRg1
UniProt Protein Name:Probable G-protein coupled receptor 139
UniProt Synonym Protein Names:G(q)-coupled orphan receptor GPRg1; G-protein-coupled receptor PGR3
Protein Family:Probable G-protein coupled receptor
UniProt Gene Name:GPR139  
UniProt Entry Name:GP139_HUMAN
Anti-GPR139 Antibody (CAB15946)Western blot analysis of extracts of various cell lines, using GPR139 antibody (CAB15946) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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