Cell Biology Antibodies 6
Anti-GNGT1 Antibody (CAB15675)
- SKU:
- CAB15675
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-GNGT1 Antibody |
Antibody SKU: | CAB15675 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-45 of human GNGT1 (NP_068774.1). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse eye, Rat eye |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-45 of human GNGT1 (NP_068774.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MPVI NIED LTEK DKLK MEVD QLKK EVTL ERML VSKC CEEV RDYV E |
Gene ID: | 2792 |
Uniprot: | P63211 |
Cellular Location: | Cell membrane, Cytoplasmic side, Lipid-anchor |
Calculated MW: | 8kDa |
Observed MW: | 10kDa |
Synonyms: | GNGT1, GNG1 |
Background: | This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. |
UniProt Protein Function: | G-gamma t1: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family. |
UniProt Protein Details: | Protein type:G protein; G protein, heterotrimeric gamma; G protein, heterotrimeric Chromosomal Location of Human Ortholog: 7q21.3 Cellular Component: plasma membrane Molecular Function:GTPase activity; protein binding Biological Process: regulation of rhodopsin mediated signaling; rhodopsin mediated signaling |
NCBI Summary: | This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. [provided by RefSeq, Jul 2016] |
UniProt Code: | P63211 |
NCBI GenInfo Identifier: | 52783592 |
NCBI Gene ID: | 2792 |
NCBI Accession: | P63211.2 |
UniProt Secondary Accession: | P63211,O43835, Q08447, Q16026, Q6LCP6, A4D1H2, |
UniProt Related Accession: | P63211 |
Molecular Weight: | 8,496 Da |
NCBI Full Name: | Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
NCBI Synonym Full Names: | G protein subunit gamma transducin 1 |
NCBI Official Symbol: | GNGT1 |
NCBI Official Synonym Symbols: | GNG1 |
NCBI Protein Information: | guanine nucleotide-binding protein G(T) subunit gamma-T1 |
UniProt Protein Name: | Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
UniProt Synonym Protein Names: | Transducin gamma chain |
UniProt Gene Name: | GNGT1 |
UniProt Entry Name: | GBG1_HUMAN |
View AllClose