Cell Biology Antibodies 8

Anti-GAS2L1 Antibody (CAB2143)

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SKU:
CAB2143
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GAS2L1 Antibody
Antibody SKU:CAB2143
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 130-400 of human GAS2L1 (NP_006469.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:A673, 22Rv1
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 130-400 of human GAS2L1 (NP_006469.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RKNE KSVV LCLL EVAR RGAR LGLL APRL VQFE QEIE RELR AAPP APNA PAAG EDTT ETAP APGT PARG PRMT PSDL RNLD ELVR EILG RCTC PDQF PMIK VSEG KYRV GDSS LLIF VRVL RSHV MVRV GGGW DTLE HYLD KHDP CRCS STAH RPPQ PRVC TFSP QRVS PTTS PRPA SPVP GSER RGSR PEMT PVSL RSTK EGPE TPPR PRDQ LPPH PRSR RYSG DSDS SASS AQSG PLGT RSDD TGTG PRRE RPSR RLTT GTPA SPRR PPA
Gene ID:10634
Uniprot:Q99501
Cellular Location:Cytoplasm, cytoskeleton
Calculated MW:34kDa/36kDa/48kDa/72kDa
Observed MW:58kDa
Synonyms:GAS2L1, GAR22
Background:This gene encodes a member of the growth arrest-specific 2 protein family. This protein binds components of the cytoskeleton and may be involved in mediating interactions between microtubules and microfilaments. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 9.
UniProt Protein Function:GAS2L1: Seems to be involved in the cross-linking of microtubules and microfilaments. Belongs to the GAS2 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: microtubule; cytoskeleton; cytoplasm; stress fiber

Molecular Function:microtubule binding; cytoskeletal adaptor activity; thyroid hormone receptor binding

Biological Process: negative regulation of erythrocyte differentiation; regulation of cell cycle; negative regulation of microtubule depolymerization; negative regulation of cell growth; cell cycle arrest; cellular response to starvation; microtubule bundle formation

NCBI Summary:This gene encodes a member of the growth arrest-specific 2 protein family. This protein binds components of the cytoskeleton and may be involved in mediating interactions between microtubules and microfilaments. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Jul 2013]
UniProt Code:Q99501
NCBI GenInfo Identifier:73915341
NCBI Gene ID:10634
NCBI Accession:Q99501.2
UniProt Secondary Accession:Q99501,Q8JZP9,
UniProt Related Accession:Q99501
Molecular Weight:681
NCBI Full Name:GAS2-like protein 1
NCBI Synonym Full Names:growth arrest-specific 2 like 1
NCBI Official Symbol:GAS2L1  
NCBI Official Synonym Symbols:GAR22  
NCBI Protein Information:GAS2-like protein 1; GAS2-related protein on chromosome 22; growth arrest-specific protein 2-like 1
UniProt Protein Name:GAS2-like protein 1
UniProt Synonym Protein Names:GAS2-related protein on chromosome 22; Growth arrest-specific protein 2-like 1
UniProt Gene Name:GAS2L1  
UniProt Entry Name:GA2L1_HUMAN
Anti-GAS2L1 Antibody (CAB2143)Western blot analysis of extracts of various cell lines, using GAS2L1 antibody (CAB2143) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
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