Cell Biology Antibodies 1

gamma-Catenin Rabbit Polyclonal Antibody (CAB0963)

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SKU:
CAB0963
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
PG, DP3, PDGB, PKGB, CTNNG, DPIII, γ-Catenin
Research Use:
Cell Biology
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Description

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gamma-Catenin Antibody (CAB0963)

The gamma-Catenin Antibody (CAB0963) is a high-quality antibody developed for reliable detection and analysis of target proteins. JUP is a key component of cell-cell adhesion complexes and is involved in maintaining tissue integrity and signaling pathways in various cell types.This antibody, generated in rabbits, is highly specific to JUP in human samples and has been validated for use in Western blot applications. By binding to JUP, researchers can detect and analyze the protein in different cell types, making it ideal for studies in cell biology, developmental biology, and cancer research.

This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:gamma-Catenin Antibody
SKU:CAB0963
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MEVM NLME QPIK VTEW QQTY TYDS GIHS GANT CVPS VSSK GIME EDEA CGRQ YTLK KTTT YTQG VPPS QGDL EYQM STTA RAKR VREA MCPG VSGE DSSL LLAT QVEG QATN LQRL AEPS QLLK SAIV HLIN YQDD AELA TRAL PELT KLLN DEDP VVVT KAAM IVNQ LSKK EASR RALM GSPQ LVAA VVRT MQNT SDLD TARC TTSI LHNL SHHR EGLL AIFK SGGI PALV RMLS SPVE SVLF YAIT TLHN LLLY QEGA KMAV RLAD GLQK MVPL LNKN NPKF LAIT TDCL QLLA YGNQ
Tested Applications:WB IP ELISA
Recommended Dilution:
WB1:500 - 1:2000
IP0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PG, DP3, PDGB, PKGB, CTNNG, DPIII, γ-Catenin
Positive Sample:MCF7, 293T, Mouse lung
Cellular Localization:Cell Junction, Cytoplasm, Membrane, Peripheral Membrane Protein, Adherens Junction, Cytoskeleton, Desmosome.
Calculated MW:82kDa
Observed MW:82kDa

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.

Purification MethodAffinity purification
Gene ID3728
RRIDAB_2757484
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using γ-Catenin Rabbit pAb (CAB0963) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020).
Product ImageImmunoprecipitation analysis of 200 μg extracts of MCF-7 cells, using 3 μg γ-Catenin antibody (CAB0963). Western blot was performed from the immunoprecipitate using γ-Catenin antibody (CAB0963) at a dilution of 1:1000.
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