Cell Biology Antibodies 16
Anti-FTSJ3 Antibody (CAB9994)
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- SKU:
- CAB9994
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FTSJ3 Antibody |
| Antibody SKU: | CAB9994 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 608-847 of human FTSJ3 (NP_060117.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human |
| Positive Samples: | A375, HeLa, MCF7, HT-1080 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 608-847 of human FTSJ3 (NP_060117.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EGEE KDGI SDSD SSTS SEEE ESWE PLRG KKRS RGPK SDDD GFEI VPIE DPAK HRIL DPEG LALG AVIA SSKK AKRD LIDN SFNR YTFN EDEG ELPE WFVQ EEKQ HRIR QLPV GKKE VEHY RKRW REIN ARPI KKVA EAKA RKKR RMLK RLEQ TRKK AEAV VNTV DISE REKV AQLR SLYK KAGL GKEK RHVT YVVA KKGV GRKV RRPA GVRG HFKV VDSR MKKD QRAQ QRKE QKKK HKRK |
| Gene ID: | 117246 |
| Uniprot: | Q8IY81 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 96kDa |
| Observed MW: | 125kDa |
| Synonyms: | FTSJ3, EPCS3, SPB1 |
| Background: | Although the function of this gene is not known, the existence of this gene is supported by mRNA and EST data. A possible function of the encoded protein can be inferred from amino acid sequence similarity to the E.coli FtsJ protein and to a mouse protein possibly involved in embryogenesis. |
| UniProt Protein Function: | FTSJ3: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA. Belongs to the methyltransferase superfamily. RlmE family. |
| UniProt Protein Details: | Protein type:EC 2.1.1.-; Methyltransferase; RNA-binding; Nucleolus; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: nucleolus; nucleus Molecular Function:protein binding; rRNA (guanine) methyltransferase activity; rRNA (uridine-2'-O-)-methyltransferase activity Biological Process: maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); rRNA methylation |
| NCBI Summary: | Although the function of this gene is not known, the existence of this gene is supported by mRNA and EST data. A possible function of the encoded protein can be inferred from amino acid sequence similarity to the E.coli FtsJ protein and to a mouse protein possibly involved in embryogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8IY81 |
| NCBI GenInfo Identifier: | 296452883 |
| NCBI Gene ID: | 117246 |
| NCBI Accession: | Q8IY81.2 |
| UniProt Secondary Accession: | Q8IY81,Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6, B2RCA5, D3DU22 |
| UniProt Related Accession: | Q8IY81 |
| Molecular Weight: | 96,558 Da |
| NCBI Full Name: | pre-rRNA processing protein FTSJ3 |
| NCBI Synonym Full Names: | FtsJ homolog 3 |
| NCBI Official Symbol: | FTSJ3 |
| NCBI Official Synonym Symbols: | SPB1; EPCS3 |
| NCBI Protein Information: | pre-rRNA processing protein FTSJ3 |
| UniProt Protein Name: | pre-rRNA processing protein FTSJ3 |
| UniProt Synonym Protein Names: | 2'-O-ribose RNA methyltransferase SPB1 homolog |
| Protein Family: | pre-rRNA processing protein |
| UniProt Gene Name: | FTSJ3 |
| UniProt Entry Name: | SPB1_HUMAN |
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