Immunology Antibodies 1

Fibrinogen alpha chain (FGA) Rabbit Polyclonal Antibody (CAB1453)

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SKU:
CAB1453
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Reactivity:
Human, Mouse, Rat
Synonyms:
Fib2, Fibrinogen alpha chain (FGA)
Research Use:
Immunology
Frequently bought together:

Description

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Fibrinogen alpha chain (FGA) Antibody (CAB1453)

The Fibrinogen alpha chain (FGA) Antibody (CAB1453) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed through immunization of rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications.The FGA Polyclonal Antibody binds to the FGA protein, allowing for accurate detection and analysis in a variety of cell types. This makes it an ideal tool for researchers studying hemostasis, thrombosis, and related conditions such as cardiovascular diseases and coagulation disorders.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Fibrinogen alpha chain (FGA) Antibody
SKU:CAB1453
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:WGTF EEVS GNVS PGTR REYH TEKL VTSK GDKE LRTG KEKV TSGS TTTT RRSC SKTV TKTV IGPD GHKE VTKE VVTS EDGS DCPE AMDL GTLS GIGT LDGF RHRH PDEA AFFD TAST GKTF PGFF SPML GEFV SETE SRGS ESGI FTNT KE
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:Fib2, Fibrinogen alpha chain (FGA)
Positive Sample:HepG2, Mouse liver, Rat liver
Cellular Localization:Secreted.
Calculated MW:95kDa
Observed MW:95kDa/60-70kDa

This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.

Purification MethodAffinity purification
Gene ID2243
RRIDAB_2761406
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Fibrinogen alpha chain (FGA) Rabbit pAb (CAB1453) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human placenta using Fibrinogen alpha chain (Fibrinogen alpha chain (FGA)) Rabbit pAb (CAB1453) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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