Cell Biology Antibodies 4
Anti-FCRL5 Antibody (CAB13803)
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- SKU:
- CAB13803
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-FCRL5 Antibody |
| Antibody SKU: | CAB13803 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-190 of human FCRL5 (NP_001182317.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, PC-12, SP2/0 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-190 of human FCRL5 (NP_001182317.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QFAR TPRP IIFL QPPW TTVF QGER VTLT CKGF RFYS PQKT KWYH RYLG KEIL RETP DNIL EVQE SGEY RCQA QGSP LSSP VHLD FSSA SLIL QAPL SVFE GDSV VLRC RAKA EVTL NNTI YKND NVLA FLNK RTDF HIPH ACLK DNGA YRCT GYKE SCCP VSSN TVKI QVQE PFT |
| Gene ID: | 83416 |
| Uniprot: | Q96RD9 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
| Calculated MW: | 14kDa/17kDa/65kDa/83kDa/106kDa |
| Observed MW: | 106kDa |
| Synonyms: | FCRL5, BXMAS1, CD307, CD307e, FCRH5, IRTA2, PRO820 |
| Background: | This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| UniProt Protein Function: | FCRL5: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32). 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell surface Chromosomal Location of Human Ortholog: 1q21 Cellular Component: receptor complex |
| NCBI Summary: | This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010] |
| UniProt Code: | Q96RD9 |
| NCBI GenInfo Identifier: | 296439341 |
| NCBI Gene ID: | 83416 |
| NCBI Accession: | Q96RD9.3 |
| UniProt Secondary Accession: | Q96RD9,Q495Q2, Q495Q4, Q5VYK9, Q6UY46, A0N0M2, B7WNT9 B7WP94, |
| UniProt Related Accession: | Q96RD9 |
| Molecular Weight: | |
| NCBI Full Name: | Fc receptor-like protein 5 |
| NCBI Synonym Full Names: | Fc receptor like 5 |
| NCBI Official Symbol: | FCRL5 |
| NCBI Official Synonym Symbols: | CD307; FCRH5; IRTA2; BXMAS1; CD307e; PRO820 |
| NCBI Protein Information: | Fc receptor-like protein 5 |
| UniProt Protein Name: | Fc receptor-like protein 5 |
| UniProt Synonym Protein Names: | BXMAS1; Fc receptor homolog 5; FcRH5; Immune receptor translocation-associated protein 2; CD_antigen: CD307e |
| Protein Family: | Fc receptor-like protein |
| UniProt Gene Name: | FCRL5 |
| UniProt Entry Name: | FCRL5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FCRL5 antibody (CAB13803) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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