Immunology Antibodies 1
Anti-FBXO38 Antibody (CAB10328)
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- SKU:
- CAB10328
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-FBXO38 Antibody |
| Antibody SKU: | CAB10328 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human FBXO38 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa |
| Immunogen: | Recombinant protein of human FBXO38 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 81545 |
| Uniprot: | Q6PIJ6 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 210KDa |
| Observed MW: | 210kDa |
| Synonyms: | FBXO38, Fbx38, HMN2D, MOKA, SP329 |
| Background: | This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | FBX38: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. May coactivate KLF7, but does not seem to promote KLF7 ubiquitination. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 5q32 Disease: Neuronopathy, Distal Hereditary Motor, Type Iid |
| NCBI Summary: | This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
| UniProt Code: | Q6PIJ6 |
| NCBI GenInfo Identifier: | 116241362 |
| NCBI Gene ID: | 81545 |
| NCBI Accession: | Q6PIJ6.3 |
| UniProt Secondary Accession: | Q6PIJ6,Q6PK72, Q7Z2U0, Q86VN3, Q9BXY6, Q9H837, Q9HC40 |
| UniProt Related Accession: | Q6PIJ6 |
| Molecular Weight: | 134kDa |
| NCBI Full Name: | F-box only protein 38 |
| NCBI Synonym Full Names: | F-box protein 38 |
| NCBI Official Symbol: | FBXO38 |
| NCBI Official Synonym Symbols: | MOKA; Fbx38; HMN2D; SP329 |
| NCBI Protein Information: | F-box only protein 38 |
| UniProt Protein Name: | F-box only protein 38 |
| UniProt Synonym Protein Names: | Modulator of KLF7 activity homolog; MoKA |
| Protein Family: | F-box only protein |
| UniProt Gene Name: | FBXO38 |
 | Western blot analysis of extracts of HeLa cells, using FBXO38 Rabbit pAb (CAB10328) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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