Cell Death Antibodies 2
Anti-FAIM Antibody (CAB17176)
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- SKU:
- CAB17176
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-FAIM Antibody |
| Antibody SKU: | CAB17176 |
| Antibody Size: | 20uL, 50 uL |
| Application: | IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human FAIM (NP_060617.1). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human FAIM (NP_060617.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTDL VAVW DVAL SDGV HKIE FEHG TTSG KRVV YVDG KEEI RKEW MFKL VGKE TFYV GAAK TKAT INID AISG FAYE YTLE INGK SLKK YMED RSKT TNTW VLHM DGEN FRIV LEKD AMDV WCNG KKLE TAGE FVDD GTET HFSI GNHD CYIK AVSS GKRK EGII HTLI VDNR EIPE IAS |
| Gene ID: | 55179 |
| Uniprot: | Q9NVQ4 |
| Cellular Location: | |
| Calculated MW: | 20kDa/22kDa/24kDa |
| Observed MW: | Refer to figures |
| Synonyms: | FAIM, FAIM1 |
| Background: | The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | FAIM: Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Belongs to the FAIM1 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 3q22.3 Cellular Component: cytoplasm Biological Process: apoptosis; negative regulation of apoptosis |
| NCBI Summary: | The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
| UniProt Code: | Q9NVQ4 |
| NCBI GenInfo Identifier: | 38503210 |
| NCBI Gene ID: | 55179 |
| NCBI Accession: | Q9NVQ4.1 |
| UniProt Related Accession: | Q9NVQ4 |
| Molecular Weight: | 20kDa |
| NCBI Full Name: | Fas apoptotic inhibitory molecule 1 |
| NCBI Synonym Full Names: | Fas apoptotic inhibitory molecule |
| NCBI Official Symbol: | FAIM |
| NCBI Official Synonym Symbols: | FAIM1 |
| NCBI Protein Information: | fas apoptotic inhibitory molecule 1 |
| UniProt Protein Name: | Fas apoptotic inhibitory molecule 1 |
| Protein Family: | Fas apoptotic inhibitory molecule |
| UniProt Gene Name: | FAIM |
| UniProt Entry Name: | FAIM1_HUMAN |
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