Description
Product Name: | FAF2 Rabbit pAb |
Product Code: | CAB20475 |
Size: | 50uL, 100uL |
Synonyms: | ETEA, UBXD8, UBXN3B |
Applications: | WB, IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human FAF2. |
Applications: | WB, IF |
Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HeLa, 293T, Mouse testis, Mouse brain, Rat liver |
Immunogen: | Recombinant protein of human FAF2. |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 23197 |
Uniprot: | Q96CS3 |
Calculated MW: | 52kDa |
Observed MW: | 53KDa |
UniProt Protein Function: | ETEA: May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 5q35.2 Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum; lipid particle Molecular Function:protein binding; ubiquitin binding; lipase inhibitor activity; ubiquitin protein ligase binding Biological Process: negative regulation of catalytic activity; response to unfolded protein |
NCBI Summary: | The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96CS3 |
NCBI GenInfo Identifier: | 74731375 |
NCBI Gene ID: | 23197 |
NCBI Accession: | Q96CS3.2 |
UniProt Secondary Accession: | Q96CS3,O94963, Q8IUF2, Q9BRP2, Q9BVM7, |
UniProt Related Accession: | Q96CS3 |
Molecular Weight: | 52,623 Da |
NCBI Full Name: | FAS-associated factor 2 |
NCBI Synonym Full Names: | Fas associated factor family member 2 |
NCBI Official Symbol: | FAF2 |
NCBI Official Synonym Symbols: | ETEA; UBXD8; UBXN3B |
NCBI Protein Information: | FAS-associated factor 2; UBX domain containing 8; UBX domain protein 3B; UBX domain-containing protein 3B; UBX domain-containing protein 8; expressed in T-cells and eosinophils in atopic dermatitis |
UniProt Protein Name: | FAS-associated factor 2 |
UniProt Synonym Protein Names: | Protein ETEA; UBX domain-containing protein 3B; UBX domain-containing protein 8 |
Protein Family: | FAS-associated factor |
UniProt Gene Name: | FAF2 |
UniProt Entry Name: | FAF2_HUMAN |