The Exportin 2 (XPO2) Monoclonal Antibody (CAB1041) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.Exportin-2 plays a crucial role in the regulation of cellular processes by controlling the transport of proteins out of the nucleus. Studies have shown that dysregulation of XPO2 can lead to various diseases, including cancer and neurodegenerative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
Exportin 2 (XPO2) Monoclonal Antibody
SKU:
CAB1041
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC1856
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CAS, CSE1, XPO2, Exportin 2 (XPO2)
Positive Sample:
HeLa, 293T, Jurkat, Mouse testis, Mouse thymus
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
110kDa
Observed MW:
105kDa
CSE1L (Chromosome Segregation 1-Like) is located on 20q13.13, and encodes a 971-amino-acid protein. It associates with microtubules and mitotic spindles, and is also considered to have a role in tumor progression. The CSE1L protein includes a nuclear localization signal allowing for transport into the nucleus via the importin-alpha/beta heterodimer. In addition, CSE1L plays roles in cell proliferation and apoptosis.
Purification Method
Affinity purification
Gene ID
1434
RRID
AB_2861493
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Exportin 2 (XPO2) Rabbit mAb (CAB1041) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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