Anti-eIF4EBP3 Antibody (CAB9913)
- SKU:
- CAB9913
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG
- Synonyms:
- EIF4EBP3
- Synonyms:
- 4E-BP3
- Synonyms:
- 4EBP3
Description
| Product Name: | eIF4EBP3 Mouse mAb |
| Product Code: | CAB9913 |
| Size: | 50uL, 100uL |
| Synonyms: | EIF4EBP3, 4E-BP3, 4EBP3 |
| Applications: | WB |
| Reactivity: | Transfected |
| Host Species: | Mouse |
| Immunogen: | Recombinant protein of human eIF4EBP3 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Transfected |
| Immunogen: | Recombinant protein of human eIF4EBP3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8637 |
| Uniprot: | O60516 |
| Calculated MW: | 10kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | 4E-BP3: Regulates eIF4E activity by preventing its assembly into the eIF4F complex. EIF4EBP3 interacts with EIF4E. Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus. Belongs to the eIF4E-binding protein family. |
| UniProt Protein Details: | Protein type:Translation; Translation initiation Chromosomal Location of Human Ortholog: 5q31.3 Cellular Component: cytoplasm; membrane Molecular Function:eukaryotic initiation factor 4E binding; protein binding Biological Process: negative regulation of translational initiation |
| NCBI Summary: | This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Oct 2010] |
| UniProt Code: | O60516 |
| NCBI GenInfo Identifier: | 4503537 |
| NCBI Gene ID: | 8637 |
| NCBI Accession: | NP_003723.1 |
| UniProt Related Accession: | O60516 |
| Molecular Weight: | 26.87kD |
| NCBI Full Name: | eukaryotic translation initiation factor 4E-binding protein 3 |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 4E binding protein 3 |
| NCBI Official Symbol: | EIF4EBP3 |
| NCBI Official Synonym Symbols: | 4EBP3; 4E-BP3 |
| NCBI Protein Information: | eukaryotic translation initiation factor 4E-binding protein 3 |
| UniProt Protein Name: | Eukaryotic translation initiation factor 4E-binding protein 3 |
| Protein Family: | Eukaryotic translation initiation factor 4E-binding protein |
| UniProt Gene Name: | EIF4EBP3 |
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