Anti-EIF4A1/EIF4A2/EIF4A3 Antibody (CAB20251)
- SKU:
- CAB20251
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
| Product Name: | EIF4A1/EIF4A2/EIF4A3 Rabbit pAb |
| Product Code: | CAB20251 |
| Size: | 50uL, 100uL |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human EIF4A1/EIF4A2/EIF4A3. |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HeLa, HepG2, MCF7, C2C12, Mouse brain, Rat brain |
| Immunogen: | A synthetic peptide of human EIF4A1/EIF4A2/EIF4A3. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 1973/1974/9775 |
| Uniprot: | P60842/Q14240/P38919 |
| Observed MW: | 46KDa |
| UniProt Protein Function: | ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. |
| UniProt Code: | P60842 |
| NCBI GenInfo Identifier: | 46397463 |
| NCBI Gene ID: | 1973 |
| NCBI Accession: | P60842.1 |
| UniProt Secondary Accession: | P60842,P04765, Q5U018, Q61516, B2R6L8, D3DTP9, J3QLC4 |
| UniProt Related Accession: | P60842 |
| Molecular Weight: | 39,548 Da |
| NCBI Full Name: | Eukaryotic initiation factor 4A-I |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 4A1 |
| NCBI Official Symbol: | EIF4A1 |
| NCBI Official Synonym Symbols: | DDX2A; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I |
| NCBI Protein Information: | eukaryotic initiation factor 4A-I |
| UniProt Protein Name: | Eukaryotic initiation factor 4A-I |
| UniProt Synonym Protein Names: | ATP-dependent RNA helicase eIF4A-1 |
| Protein Family: | Eukaryotic initiation factor |
| UniProt Gene Name: | EIF4A1 |
| UniProt Entry Name: | IF4A1_HUMAN |
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